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Symbol
Name
ID
Nos3
nitric oxide synthase 3, endothelial cell
MGI:97362
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Anosmia
Stroke
Ischemic stroke
Photophobia
Abnormality of the nervous system
Depression
Irritability
Anxiety
Phonophobia
Excessive daytime somnolence
Obstructive sleep apnea
Snoring
Migraine with aura
Migraine without aura
Focal impaired awareness seizure
Disease(s) Associated with NOS3
Behcet's disease
cystic fibrosis
migraine
obstructive sleep apnea
sickle cell anemia

Mouse Phenotypes
nervous system phenotype
abnormal seizure response to inducing agent
abnormal blood-brain barrier function
increased susceptibility to neuronal excitotoxicity
abnormal neuronal precursor proliferation
abnormal dentate gyrus morphology
abnormal neuron morphology
abnormal nervous system physiology
decreased neurotransmitter release
Availability Mouse Genotype
Nos3tm1Plh/Nos3tm1Plh *
Nos3tm1Unc/Nos3tm1Unc

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory